Printable page in A4 size Matthew C.L. Phillips
Waikato Hospital · Neurology Department
"Metabolic Strategies in Healthcare: A New Era"
Abstract
Disease-centric Medicine
Modern healthcare systems are founded on a disease-centric paradigm, which has conferred many notable successes against infectious disorders in the past. Our disease-centric paradigm regards these disorders as distinct disease processes, caused and driven by disease targets that must be suppressed or eliminated to clear the disease.
Health-centric Medicine
Today’s leading causes of death are dominated by non-infectious “lifestyle” disorders, broadly represented by the metabolic syndrome, atherosclerosis, cancer, and neurodegeneration. By contrast, a health-centric paradigm recognizes the lifestyle disorders as a series of hormonal and metabolic responses to a singular, lifestyle-induced disease of mitochondria dysfunction, a disease target that must be restored to improve health, which may be defined as optimized mitochondria function.
Metabolic Strategies Restore Health
Seen from a health-centric perspective, most drugs target a response rather than the disease, whereas metabolic strategies, such as fasting and carbohydrate-restricted diets, aim to restore mitochondria function, mitigating the impetus that underlies and drives the lifestyle disorders.
Evidence in New Science
Substantial human evidence indicates either strategy can effectively mitigate the metabolic syndrome.
Preliminary evidence also indicates potential benefits in atherosclerosis, cancer, and neurodegeneration.
Given the existing evidence, integrating metabolic strategies into modern healthcare systems should be identified as a global health priority.
"Metabolic Strategies in Healthcare: A New Era"
(35 minutes)
Matthew C.L. Phillips - 15 July 2022
"Metabolic Strategies in Healthcare: A New Era" The Paper
You can read and print the paper here. (18 Pages)(150 Scientific Papers)
Link to the Science
Too few people read the science. It's not a mystery. Especially on topics that interest you, you can read enough to get important new understanding. Then you need to talk to your doctor, registered nurse, or perhaps your chemist. Here is the link to the science.
This is new, 2022
Time-Restricted Ketogenic Diet in Huntington's Disease: A Case Study
July, 2022
By Matthew C. L. Phillips1, Eileen J. McManus1, Martijn Brinkhuis and Beatriz Romero-Ferrandol
Matthew Phillips Talk on Parkinson's Dietary Study
Matthew C. L. Phillips (70 minutes)
Published by:Parkinsons New Zealand - January, 2019
Is there an “optimal” diet for Parkinson’s? This question has been debated for years. On one hand, low-fat, high-carbohydrate diets may increase brain dopamine, an important chemical deficient in Parkinson’s. On the other hand, a high-fat, low-carbohydrate “ketogenic” diet may enhance the brain mitochondria that produce energy for brain cells.
Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial
August, 2018
By Matthew C L Phillips, Deborah K J Murtagh, Linda J Gilbertson, Fredrik J S Asztely, Christopher D P Lynch
Dr Matthew Phillips - Parkinson's, Fasting, and Ketogenic Diets
A more technical talk on the study above.
Dr Matthew Phillips (30 minutes)
Published by:Nutrition In Parkinson's - Feb 2021
Mitochondria's Role in Alzheimer's - with Dr. Matthew Phillips
Dr David Perlmutter (28 minutes)
Published by:DavidPerlmutterMD -
As many of you are aware, the ketogenic diet has been demonstrated to enhance mitochondrial function. As such, it should be considered as a candidate for treating a disease like Parkinson's. In fact, this is the subject of a recent interventional trial in which actual Parkinson's patients were placed on a ketogenic diet, under the direction of Dr. Matthew Phillips.
Bret Scher with Dr Matthew Phillips (38 minutes)
Published by: Metabolic Mind
Metabolic therapy in glioblastoma: Ancestral strategies
Dr Matthew Philips (51 minutes)
Published by:PREKURE - Prevention is Cure. - September, 2023
Can the keto diet influence brain cancer? Clinical and Research Neurologist Dr Matthew Philips spoke at the Future of Medicine Conference 2023, about his research into utilising fasting and low-carb, high-fat ketogenic diets to help those with glioblastoma.
