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Assistant Professor Ken Sikaris - Chemical Pathologist

Main web page for: Dr Ken Sikaris

A University of Melbourne graduate, Dr Sikaris trained at the Royal Melbourne, Queen Victoria, Prince Henry's and Heidelberg Repatriation Hospitals. He obtained fellowships from the Royal College of Pathologists of Australasia (RCPA) and the Australasian Association of Clinical Biochemists (AACB) in 1992 and 1997 respectively.

I'm helping anyone who wants to understand blood tests.

Fatty Liver & Chemical Pathology

Dr Ken Sikaris (26 minutes)

Published by: Low Carb Downunder - 23 Aug 2019

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Most heart attacks occur while PRE-DIABETIC HbA1c below 6.5%

Dr Ken Sikaris (4 minutes)

Published by: Doctors to Trust - 12 Sept 2023

Randomized, control trials in low carb for type 2 diabetes creates lower triglycerides; HDL rises; and HbA1c is lower.
This is much better than the high carb; low fat diet, once recommended.
Red color in blood is hemoglobin - sugar sticks to red blood cells [that is HbA1c]
-hemoglobin stays in blood for about 3 months so HbA1c is measure of glucose for past 3 months.

If you go on low carb eating, HbA1c won't change for awhile...
"My own HbA1c was 5.4; fell to 5.2 after 3 months but, after 1 year, it is now 4.8"
As your HbA1c rises, so does coronary heart disease risk.
-Above 6.5%: diabetes is diagnosed and there is increased risk of eye and & kidney disease.

Heart risk did not start when you hit 6.5%, but started way back at 5.5...
-most people who have heart attacks are not diabetic, they are prediabetic, and the heart attack got them before diabetes was diagnosed.

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Without CHOLESTEROL: -cells fall apart

Dr Ken Sikaris (4 minutes)

Published by: Doctors to Trust - 6 Sept 2023

Important lipoprotein particles of cholesterol in blood... -liver makes VLDL which is full triglycerides & fat
In blood, triglycerides taken out into muscle and other tissues.
The original VLDL gets smaller & smaller until a cholesterol-rich LDL particle is left.
VLDL made in the liver is always triglyceride rich.
Triglycerides are used in the tissues and their loss creates LDL which is cholesterol rich.
-NORMAL LDL goes straight back to liver and is reprocessed. Damaged LDL might not be accepted by the liver and remain in the bloodstream.

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Blood Tests for Iron Status

Dr Ken Sikaris (33 minutes)

Published by: Low Carb Downunder - 6 Jun 2021

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HEART ATTACK PREDICTOR?

Dr Ken Sikaris (7 minutes)

Published by: Doctors to Trust - 9 Feb 2025

If triglycerides are over 1.5, you will have sdLDL…
-To be confident that you are free of sdLDL, are your triglyceride should be less than 1.
That is likely if on ultra low carb eating [less than 50g / day]

What's the best lipid marker ratio to predict sdLDL? -TC/HDL -better than TG or HDL

TC/HDL is also the best predictor of cardiovascular disease
-Other tests, non-HDL, apoB, or apolipoprotein A-1 are no better than TC/HDL

There is a high correlation between TC and LDL [.83 & .88]…
-in the ratio TC/HDL, don't use HDL, use 1/HDL -1/HDL correlates with TG [.89]

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Analysing The Cholesterol Message

Dr Ken Sikaris (57 minutes)

Published by: Low Carb Downunder - 2 Feb 2025

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